Wednesday, December 16, 2009

Thrombocytopenic Purpura More Condition_symptoms Thrombocytopenic Purpura?

Thrombocytopenic purpura? - thrombocytopenic purpura more condition_symptoms

What is it?

Posted by Weiland Ceja at 1:39 PM

1 comment:

  1. L_H Qutub(Retired)December 21, 2009 at 11:38 AM

    There are two types:
    1) idiopathic thrombocytopenic purpura.
    Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenic purpura is well known Primary thrombocytopenic purpura and autoimmune disease as isolated thrombocytopenia with normal bone marrow and the absence of other defined causes of thrombocytopenia. On 2 Diseases manifesting itself as an acute illness in children and chronic diseases in adults.

    ITP is connected to a decline in the number of circulating platelets in the absence of exposure to toxic substances or disease with a low number of platelets.
    * Common physical findings include:

    Petechiae or intangible, which mainly occur in regions dependent on

    hemorrhagic blisters on mucous membranes or

    Purpura

    Bleeding gums

    or signs of gastrointestinal bleeding

    Menometrorrhagia or menorrhagia

    or retinal hemorrhages

    No evidence of intracranial hemorrhage, with possible neurological symptoms

    Spleen not palpable or: The prevalence of palpable spleen in patients with ITP is approximately the same as non-ITP population (3% of adults) 12% in children.

    Spontaneous bleeding or if the platelet count below 20,000 / mm3.

    Causes:

    * The immunoglobulin G (IgG) autoantibodies on the platelet surface

    2) thrombotic thrombocytopenic purpura (TTP) is a potentially fatal disease, which is a multisystemic a true medical emergency. TTP Moschcowitz first described in 1924, said the 16-year-old woman with anemia, petechiae, microscopic hematuria, and at autopsy, disseminated fibrin thrombi. Since then, the pathophysiology, etiology and treatment of TTP have been expanded. These potentially life-threatening and that a positive outcome if detected early, and if medical intervention is started early may have.

    Thrombocytopenic purpura is a syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia, neurological abnormalities, fever and renal dysfunctionIons. With the introduction of plasma exchange has improved the survival rate of about 3% before 1960 to 82%. Early initiation of plasma exchange positive results. With early detection of clinical signs, this potentially lethal disease can be treated effectively with the clinical response in many cases.

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